Colorectal Mucosa, What It Is And Many More Things: Hey guys, today I am sharing some useful information about Colorectal Mucosa. May this information helps you.
Colorectal Mucosa, What It Is And Many More Things
What Is CRC? | Colorectal Mucosa
Colorectal cancer begins in the colon. Depend on where they start. These cancers are called colon or rectal cancer. Colon and rectal cancers are often lumped together due to similarities.
The Rectum And Colon | Colorectal Mucosa
The normal structure as well as function of the colon and rectum can help understand colorectal cancer. The large intestine (or bowel) is made up of the colon and rectum (see illustration below).
The colon is a 5 foot (1.5 metre) long muscular tube that makes up the large intestine. The colon is named after the direction in which food passes through it.
The ascending colon is the first section. The cecum is a pouch where undigested food from the small intestine enters. It ascends right side of the abdomen (belly).
The transverse colon is the second section. It crosses the body from right to left. The descending colon is named so because it descends on the left.
The sigmoid colon gets its name from its “S” shape. The sigmoid colon connects rectum to the anus.
The proximal colon combines the ascending and transverse sections. The distal colon is the descending and sigmoid colon.
What Is The Colon And Rectum?
After the small intestine, the colon absorbs water and salt from the remaining food (small bowel). The waste from the colon goes into the rectum, the last 6 inches (15cm) of the digestive system.
It’s stored there until the anus. The anus has ring-shaped muscles that keep stool from coming out until they relax during a bowel movement.
How Does Colon Cancer Begin?
Colon or rectum polyps. In colon or rectum, most colorectal cancers begin as a growth. .
Some polyps might develop into cancer over time (usually years), but not all polyps do. The likelihood of a polyp becoming cancerous varies by type. Polyps come in various forms.
Adenomatous polyps (adenomas), Can turn into cancer. Adenomas are pre-cancerous because of this. Adenomas can be tubular, villous, or tubulovillous.
Hyperplastic and inflammatory polyps are more common, but not precancerous. Individuals with large (>1cm) hyperplastic polyps may require more frequent colonoscopies to detect cancer.
SSPs and TSAs, Since these polyps carry a higher risk of colorectal cancer, they are often treated as adenomas.
Other factors that may increase risk of a polyp containing cancer or developing colorectal cancer include:
- A polyp larger than 1 cm
- Polyps found in excess of 3
If the polyp has dysplasia after removal. Dysplasia is a pre-cancerous state. It means a polyp or the lining of the colon. Either rectum has cells that look abnormal but are not cancerous.
How Colon Cancer Spreads
A polyp can develop cancer and grow into the colon or rectum wall. The colon and rectum have many layers. Colorectal cancer starts in the mucosa and can spread to any or all of the other layers (see picture below).
Cancer cells in the wall can grow into blood or lymph vessels (tiny channels that carry away waste and fluid). They can then travel to nearby lymph nodes or further afield.
Colorectal cancer stage is determine by how deep it grows into the wall and if it has spread outside the colon or rectum.
Types Of Colon And Rectal Cancer
They are adenocarcinomas. It starts in cells that make mucus to lubricate the colon and rectum. This is the type of colorectal cancer that doctors usually refer to. Some adenocarcinoma subtypes, like signet ring and mucinous, have a worse prognosis than others.
Other, less common tumours can develop in the colon and rectum. These are:
Carcinoma, These come from intestinal hormone-producing cells. GI Carcinoid Tumors
GISTs, begin in the interstitial cells of Cajal, which line the colon’s wall. Some are good (not cancer). Unlike colon tumours, these can occur anywhere in the digestive tract. GI stromal tumour (GIST).
Lymphomas, are immune system cancers. Their origins are in the lymph nodes. But they can also be in the colon or rectum. Non-Hodgkin Lymphoma has information on digestive lymphomas.
This includes blood vessels, muscle layers, and connective tissues in the colon and rectum. Colon and rectal sarcomas are rare. Sarcoma Soft Tissue.